Journal Article

DZNE-2025-00595

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Will adaptive deep brain stimulation for Parkinson's disease become a real option soon? A Delphi consensus study.

Guidetti, M. ; Bocci, T. ; De Pedro Del Álamo, M. ; Deuschl, G. ; Fasano, A. ; Martinez-Fernandez, R. ; Gasca-Salas, C. ; Hamani, C. ; Krauss, J. K. ; Kühn, A. A.DZNE* ; Limousin, P. ; Little, S. ; Lozano, A. M. ; Maiorana, N. V. ; Marceglia, S. ; Okun, M. S. ; Oliveri, S. ; Ostrem, J. L. ; Scelzo, E. ; Schnitzler, A. ; Starr, P. A. ; Temel, Y. ; Timmermann, L. ; Tinkhauser, G. ; Visser-Vandewalle, V. ; Volkmann, J. ; Priori, A.

2025
Springer Nature [London]

This record in other databases:    

Please use a persistent id in citations: doi:10.1038/s41531-025-00974-5

Abstract: While conventional deep brain stimulation (cDBS) treatment delivers continuous electrical stimuli, new adaptive DBS (aDBS) technology provides dynamic symptom-related stimulation. Research data are promising, and devices are already available, but are we ready for it? We asked leading DBS experts worldwide (n = 21) to discuss a research agenda for aDBS research in the near future to allow full adoption. A 5-point Likert scale questionnaire, along with a Delphi method, was employed. In the next 10 years, aDBS will be clinical routine, but research is needed to define which patients would benefit more from the treatment; second, implantation and programming procedures should be simplified to allow actual generalized adoption; third, new adaptive algorithms, and the integration of aDBS paradigm with new technologies, will improve control of more complex symptoms. Since the next years will be crucial for aDBS implementation, the research should focus on improving precision and making programming procedures more accessible.

---

Contributing Institute(s):

1. Movement Disorders (Parkinson's disease, Dystonia) (AG Kühn)

Research Program(s):

1. 353 - Clinical and Health Care Research (POF4-353) (POF4-353)

Appears in the scientific report 2025

---

Database coverage:
; ; ; ; Article Processing Charges ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DOAJ Seal ; Essential Science Indicators ; Fees ; IF >= 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---