Journal Article

DZNE-2026-00360

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Calibration-Free GRAPE pTx Pulses for Homogeneous Spatial-Selective Excitation at 7T.

Löwen, D. (First author)DZNE* ; Pracht, E. D.DZNE* ; Veldmann, M.DZNE* ; Gras, V. ; Mauconduit, F. ; Boulant, N. ; Stöcker, T. (Last author)DZNE*

2026
Wiley-Liss New York, NY [u.a.]

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Please use a persistent id in citations: doi:10.1002/mrm.70266

Abstract: Extend the universal pulse GRAPE formalism to pulses with a defined spectral response, and apply the concept to spatial selection.We added Bloch simulations at several frequencies for each voxel to the pulse calculation to create universal spectrally-selective GRAPE pulses. With a superimposed constant gradient field spatial selection was achieved. The method was tested in slice- and slab-selective imaging experiments.Universal spatially-selective GRAPE pulses increased FA homogeneity and SNR. In 2D gradient echoes, the SNR could be increased by approximately 6% compared to CP pulses, and in a slab-selective TSE sequence, the SNR increased by 29% against k T -spokes pulses. Additionally, the slab-selective GRAPE pulse proved to be more robust against B 0 deviations and is significantly shorter in comparison to k T -spokes pulses while maintaining a similar FA homogeneity.Spatially-selective universal GRAPE pulses exhibit superior performance compared to k T -spokes pulses. These short and robust pTx pulses hold potential for enhancing a wide range of imaging applications, thereby advancing 7T MRI technology closer to clinical use.

Keyword(s): Phantoms, Imaging (MeSH) ; Humans (MeSH) ; Algorithms (MeSH) ; Magnetic Resonance Imaging: methods (MeSH) ; Signal-To-Noise Ratio (MeSH) ; Calibration (MeSH) ; Image Processing, Computer-Assisted: methods (MeSH) ; Computer Simulation (MeSH) ; Brain: diagnostic imaging (MeSH) ; GRAPE ; parallel transmission ; ultra‐high field ; universal pulses

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Contributing Institute(s):

1. MR Physics (AG Stöcker)

Research Program(s):

1. 354 - Disease Prevention and Healthy Aging (POF4-354) (POF4-354)

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Database coverage:
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; DEAL Wiley ; Essential Science Indicators ; IF < 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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